Across
- 3. diabetic ____________ is associated with degeneration of peripheral nerves
- 5. these cells secrete insulin
- 8. this hormone is released when blood glucose is too low
- 9. this kinase is activated by physiological stressors associated with obesity, stress and inflammation
- 10. phosphorylation of these amino acid residues on IRS-1 leads to insulin resistance
- 11. the insulin receptor phosphorylates targets on these amino acid residues
- 12. diabetic ___________ is the leading cause of blindness
Down
- 1. this enzyme phosphorylates glucose in the glycolysis cycle to ultimately produce ATP
- 2. insulin-producing cells are destroyed by this process in Type 1 diabetes
- 4. this biomarker reflects average blood sugar levels over the past 2-3 months
- 6. this calcium -dependent movement of insulin granules out of the cell
- 7. muscle cells express this transporter in their cell membrane to mediate glucose uptake