Across
- 2. Non‑replicating vaccine prepared from killed pathogen
- 4. Immune detection and elimination of transformed cells
- 6. Secondary immunisation enhancing immune memory
- 9. Tumour strategies to avoid immune recognition
- 10. Spread of tumour cells to distant tissues
- 12. Inhibitory pathway regulating T‑cell activation
- 13. Selection of higher‑affinity lymphocyte clones
- 14. Live vaccine with reduced pathogenicity
Down
- 1. Strength of antigen–antibody binding
- 2. Cancer treatment using immune mechanisms
- 3. Long‑term persistence of antigen‑specific lymphocytes
- 5. Novel tumour‑specific antigen arising from mutation
- 7. Induction of protective immunity without disease
- 8. Referring to determinants recognised by the immune system
- 11. Vaccine component enhancing immune activation