Across
- 2. Process of new growth in which normal cells undergo irreversible genetic change
- 9. abnormal numbers of chromosomes
- 11. Benign tumor of adipocytes
- 12. tissue growth
- 18. extreme variability in nuclear size
- 19. wide variation in cell siza
- 20. growth factor that stimulates fibroblast and increase production of collagen
- 21. tumors spread beyond the original host via physical transplantation following direct physical contact between animals of the same species
- 23. ovarian and pancreatic adenocarcinomas spread transcoelomically, resulting in multiple tumor masses throughout the abdomen
- 25. process by which the immune system identifies and kills microbially infected cells or foreign cells
Down
- 1. wide variation in cell shape
- 3. an irreversible alteration of genetic material, first step of neoplastic transformation
- 4. antigens antigens present on both tumor cells and normal cells
- 5. Development of new blood vessels
- 6. spread Tumor invade through veins to reach the vena cava, commonly sarcomas
- 7. antigens antigens restricted to tumor cells
- 8. cancerous tumors that invade locally and spread by metastasis
- 10. outgrowth of initiated cells in response to selective stimuli, second step of neoplastic transformation
- 13. nonneoplastic supporting structures like blood vessels, fibroblast, and inflammatory cells
- 14. antigens embryonic antigens normally not expressed in adult tissue
- 15. noncancerous tumors that do not invade locally nor spread
- 16. malignant transformation, third step of neoplastic transformation
- 17. development of lymphatic vasculature in tumors
- 22. tumor consisting of tumor cells termed parenchyma
- 24. notable weight loss and debility
- 26. poor cell differentiation
