Across
- 4. Seen as a collection of scarred, obliterated capillaries and accumulations of matrix material in part of the affected glomerulus. No response to corticosteroid therapy.
- 5. Hematuria (smoky brown urine), oliguria, azotemia and hypertension.
- 7. Massive proteinuria (the loss in the urine of >3.5 g of protein/day), hypoalbuminemia, edema, hyperlipidemia.
- 9. Diffuse thickening of the glomerular basement membrane and subepithelial deposits,effacement of foot processes, and the presence of spikes of basement membrane material between the immune deposits.
- 10. Nodules in the mesangium. These nodules are spherical and eosinophilic, with a central acellular area. It is pathognomonic of diabetes.
Down
- 1. Active lesions of the glomeruli include: endocapillary hypercellularity or extra-capillary proliferation (crescents), inflammation (glomerular or interstitial), fibrinoid necrosis and subendothelial deposits.
- 2. Mainly affect children (2-6) Only shows effacement of the epithelial cell (podocyte)foot processes and have complete remission within 8 weeks of corticosteroid therapy.
- 3. Diagnosis depends on serologic evidence of a rise in antibody titers to streptococcal products. Serum anti–streptolysin O antibody titers is positive.
- 6. Mesangial cell proliferation, basement membrane duplication, leukocyte infiltration, and accentuation of lobular architecture.
- 8. The most common type of primary glomerulonephritis that presents with hematuria.