Across
- 1. If SMAD is inhibited by this molecule, then it cannot get phosphorylated to make a complex and it therefore cannot get translocated to the nucleus to get EMT/proliferation/etc. started.
- 6. I'm a receptor on the immune cell that PAMP binds to / detects PAMPs on the pathogen to signal the immune cell that something foreign has pulled up
- 8. chaperone; imma take the CTFR molecule and allow it to get processed and get it inserted into the membrane. im the protein escort and I act on the CFTR protein
- 9. I'm so excited to fire up some neurons to activate the pain pathway SQUEEEE!
- 11. I'm an intracellular signalling protein that takes TGFbeta signals and carries them from the cell membrane to the nucleus
- 12. Ionotropic glutamate receptor that allows and needs all sorts of ions to flow across the membrane, membrane is depolarized. I let in calcium ions. also known as coincidence detectors. remove mg to allow ca and na while k flows out.
- 13. I help the enzymes that turn cholesterol into progesterone
- 15. a way to measure pain through activity in the nervous system
Down
- 2. potentiator; i need to bind to the channel so it can open up. i open up the CTFR protein/channel. im the channel opener and I act on the CFTR channel!
- 3. I inhibit JAK1 and JAK2 to stop crazy cytokine and interferon responses
- 4. along with theca I help to make up the corpus luteum
- 5. I'm the grandmother of steroids, and I'm made from cholesterol!
- 7. sneak me into bird feed, they won't know!
- 10. I'm the cause for your cloudy days.
- 14. I'm phosphorylated by these frat boi kinases, I dimer up with a buddy, we move into the nucleus together and I bind DNA and turn on target genes like cytokines and ISGs