Across
- 4. hydrolyze phosphorylated proteins
- 5. in the absence of insulin, the recptor exists as a ___
- 6. signal molecule
- 7. number of helices in GPCRs
- 12. small G proteins are ___, as opposed to being heterotrimeric
- 13. hormone released by ß cells of the pancreas
- 16. enzyme responsible for increasing cAMP concentration
- 17. refers to the state of the unactivated G protein
- 19. hormone that binds to the ß-adrenergic receptor
- 20. in Cholera, the G protein is constitutively ___
Down
- 1. enzyme that converts cAMP to AMP
- 2. molecules that relay info. from the receptor-ligand complex
- 3. ____ syndrome: diseases resulting from a mutation leading to a constitutively active form of PKA, resulting in excess cortisol secretion
- 8. family of proteins that calmodulin belongs to, consisting of a helix-loop-helix motif
- 9. stimulus that triggers the release of the signal molecule
- 10. number of calcium binding sites in calmodulin
- 11. one of the residues phosphorylated by PKA
- 14. calcium sensor in eukaryotic cells
- 15. number of regulatory units bound to enzymatically active form of PKA
- 18. second messenger that activates PKC