Across
- 2. Derivatives of tetracycline group drugs that lack antimicrobial action but have potent host modulating affects such as inhibiting elevated MMP's pro-inflammatory cytokines and other destructive chemical mediators.
- 5. Aim to subject subgingival bacteria to therapeutic levels of an antibacterial drug for a sustained period.
- 6. Used in medicine and dentistry to describe the lightly pulling together of wound edges from opposite sides so they appear touching.
- 7. Aims to form new cementum new functionally aligned PDL fibers and new alveolar bone.
- 11. Doses of an antibiotic that are below the normal bacterial killing or inhibiting doses.
- 15. Chlorhexidine gluconate chip is commonly sold under what brand name?
- 20. Fill in the Blank: Developement of resistant bacteria and gastrointestinal toxicity seen with antibacterial doses of the tetracyclines is ______ produced by chemically modified tetracyclines.
- 21. A condition that makes a particular treatment or procedure potentially inadvisable.
- 22. Refers to the degree the margins or edges of the surgical wound relate to each other following surgery but prior to healing.
- 23. biochemical mediators that can lead to damage of the periodontium.
- 25. Describes the union of a pathologically exposed root with connective tissue or epithelium.
- 27. Fill in the Blank: A patient with _________ expectation of periodontal surgery is considered a relative contraindication.
- 31. The healing of a periodontal wound by the reunion of the connective tissue and roots where these two tissues have been separated by surgical incision or physical injury but not by disease.
- 34. Fill in the Blank: The periodontium cannot be regenerated ___________ in all sites with current periodontal regenerative approaches.
- 36. NSAIDs reduce tissue inflammation by inhibiting the action of what?
- 37. An mouthrinse ingredient that is a good alternative for patients who cannot tolerate the side effects and allergies associated with chlorhexidine.
- 44. Tufted dental floss is great for fixed bridges distal surfaces of the last tooth in the arch proximal surfaces of widely spaced teeth and what type of embrasure spaces?
- 45. Fill in the Blank: Regeneration is healing that results in the reestablishment of the ___________ tissues that were present before the disease or damage occurred.
- 47. A situation that makes a particular treatment undoubtedly inadvisable.
- 50. Healing where the wound is first cleaned by the surgeon and left open deliberately to ensure no infection is apparent before it is closed at a later date.
- 51. Doxycycline Hyclate gel is commonly sold under what brand name?
- 52. Biologically active compounds stimulated by bacteria that activate the inflammatory response.
- 54. A condition that may make periodontal surgery inadvisable.
- 57. The most effective antimicrobial agent in mouthrinses for longterm reduction of biofilm and gingivitis.
- 58. Medications or agents such as estrogen selective estrogen receptor modulators ad bisphosphonates that reduce bone resorption and helpt to preserve bone mineral density.
- 59. The anti-inflammatory biochemical mediators include Interleukin-10 Interleukin-1ra TIMPs and what other cytokine?
- 60. Tissue that must form to close the space between the wound margins of tissues that are not closely adapted in order for epithelial cells to grow over the wound.
- 61. Meducations used to control elevated cholesterol levels and can also offer some protection against systemic inflammation.
- 62. What is the effect of Arestin on bacteria?
- 63. Provides enhanced access and visualization to the root surfaces for more thorough periodontal instrumentation.
- 64. The mechanism of action of this group of chemical agents used in mouthrinses is the disruption of the cell wall and inhibition of certain bacterial enzymes.
- 65. Fill in the Blank: When a patient taking daily doses of NSAIDs for an extended amount of time stops there can be _____________ of the bone loss seen prior to taking the drugs.
Down
- 1. This is an expectation for periodontal surgery but is not possible with nonsurgical periodontal therapy.
- 3. Healing that takes place when the margins or edges of the wound are not closely adapted or in close contact with eachother.
- 4. Refers to a patient not performing adequate biofilm control and can be a relative contraindication for periodontal surgery.
- 8. The destruction and death of bone tissue.
- 9. Modifying a patient's defense responses to help the body's defenses limit damage caused by disease.
- 10. Drugs that inhibit the resorption of bone by altering osteoclastic activity though the mechanism of action for these drugs is not fully understood.
- 12. An Matrix Metalloproteinase that can break down collagen.
- 13. A surgical procedure in which incisions are made in the gingiva or mucosa to allow for separation of the surface tissues from the underlying tooth roots and alveolar bone.
- 14. Periodontal surgery to modify the alveolar bone level or contour.
- 16. Functions as a protective mechanism that keeps bacterial infection from doing serious harm to the periodontium.
- 17. The pro-inflammatory biochemical mediators include Interleukin-1 ProstaglandinE2 Tumor Necrosis Factor Alpha Matrix Metalloproteinases and what other biochemical mediator?
- 18. Fill in the Blank: NSAIDs can reduce inflammation and inhibit _________ activity.
- 19. Initials for tissue inhibitors of matrix metalloproteinases
- 24. The process of adding specific biomolecules to the diet to improve patient health and the host response to periodontitis.
- 26. Biochemical mediators that are protective and limit the bacterial-induced inflammatory response from doing serious harm to the periodontium.
- 28. The formation of what structure can be seen in response to surgical or nonsurgical periodontal therapy.
- 29. Initials for the major potential side effect associated with bisphosphonate use.
- 30. A progressive bone disease that is characterized by a decrease in both bone mass and bone density that can lead to an increased risk of bone fractures.
- 32. The generic name for Arestin.
- 33. A deformity in the tooth-supporting alveolar bone usually resulting from periodontitis.
- 35. Minocycline hydrochloride microspheres are commonly sold under what brand name?
- 38. A tetracycline-class antibiotic drug that has been used to treat a varierty of infections and also has other benefits besides its antibiotic effect when used in lower doses.
- 39. An important characteristic of mouthrinses and dentrifices where the active ingredient continues to kill periodontal pathogens over an extended number of hours following rinsing.
- 40. Refers to the ending of inflammation and healing of the periodontal pocket and can be seen in both periodontal surgery and nonsurgical periodontal therapy.
- 41. One of the major building blocks in the periodontium whose breakdown is part of the fundamental pathology of periodontitis.
- 42. Occurs when the wound margins or edges are closely adapted to each other.
- 43. The initials for drugs that have ben used for many years to treat pain acute inflammation and chronic inflammatory conditions.
- 46. Healing of a wound by formation of tissues that do not fully restore the original architecture or original function of the body part.
- 48. Medications or agents that stimulate bone formation thereby increasing overall bone mineral density.
- 49. Unwaxed or waxed thread made of silk nylon or plastic monofilament fibers.
- 53. The reconstitution of new tissue.
- 54. Anti-inflammatory mediators derived from Omega-3 fatty acids that work to resolve inflammation to reduce the risk of tissue breakdown and attachment loss.
- 55. How many times a day should a periodontitis patient take low dose doxycycline for it to be effective?
- 56. Surgical procedures that simply cut away and remove some of the periodontal tissues.