Across
- 3. A drug that activates a receptor
- 4. the amount of drug required to produce 50% of that drug's maximal effect; the more potent the drug, the lower the dose required for a given effect.
- 8. An example of an allosteric modulator is a class of drugs called?
- 12. An example of a drug that acts on ion channels is?
- 13. An abbreviation for Transporters that facilitate active transport across a membrane and that contain a distinct ATP binding site are called
- 14. On the dose-response curve the concentration at which the effect is 50% of the maximum is called the
- 15. This term is used clinically to describe diminished responsiveness after repeated exposure to the same concentration of the drug
- 16. Drug that attaches to a receptor, but does not initiate an action
- 17. The strength of the binding interaction between a drug and its molecular target is defined as?
Down
- 1. Drug A is administered to a person that acts on a particular receptor. Unfortunately, it is given in overdose. Drug B is then administered, which blocks that receptor. The effects of drug B result in a reduction of the effect of drug A. Drug A is acting how?
- 2. Most drugs display preference for one subtype of receptor over others this is referred to as?
- 4. Relates to the mechanism of action of medicines
- 5. The ability to produce an effect on a particular target tissue
- 6. This term refers more specifically to a decrease in the response of the receptor–second messenger system and is a common feature of many receptors, it is?
- 7. the ability of a drug to achieve the desired therapeutic effect
- 9. Doug determines the relative safety of a drug in terms of a ratio between its lethal dose and its effective dose. This measure is called the therapeutic _____.
- 10. Ligands typically recognise and bind to?
- 11. Enzymes typically act as catalysts to facilitate the conversion of what into products
