Across
- 3. This term is used clinically to describe diminished responsiveness after repeated exposure to the same concentration of the drug
- 4. On the dose-response curve the concentration at which the effect is 50% of the maximum is called the
- 11. relates to the amount of chemical required to produce an effect
- 12. Drug A is administered to a person that acts on a particular receptor. Unfortunately, it is given in overdose. Drug B is then administered, which blocks that receptor. The effects of drug B result in a reduction of the effect of drug A. Drug A is as a (two-words)?
- 14. Enzymes typically act as catalysts to facilitate the conversion of what into products
Down
- 1. Relates to the mechanism of action of medicines
- 2. refers to the narrowness of a drug's range of actions on particular receptors, cellular processes or tissues
- 5. This term refers more specifically to a decrease in the response of the receptor–second messenger system and is a common feature of many receptors, it is?
- 6. A drug that activates a receptor
- 7. Ligands typically recognise and bind to?
- 8. Drug that attaches to a receptor, but does not initiate an action
- 9. the ability of a drug to achieve the desired therapeutic effect
- 10. The strength of the binding interaction between a drug and its molecular target is defined as?
- 13. Doug determines the relative safety of a drug in terms of a ratio between its lethal dose and its effective dose. This measure is called the therapeutic _____.
- 15. An abbreviation for Transporters that facilitate active transport across a membrane and that contain a distinct ATP binding site are called