Across
- 2. There was a significant 25% reduction in the rate of fatal or nonfatal stroke in hypertensive patients with LVH randomized to losartan instead of atenolol.
- 4. Lower BP associated with lower total kidney volume in PKD
- 6. Ramipril significantly reduces the rates of death, myocardial infarction, & stroke in a broad range of high-risk patients who are not known to have a low ejection fraction or heart failure.
- 7. ACE inhibitor/calcium channel blocker better than beta blocker/thiazide diuretic combination in reducing major cardiovascular outcomes in people with hypertension.
- 10. Losartan has a renoprotective effect in diabetic nephropathy
- 12. No significant reduction of SBP in resistant hypertension 6 months after renal-artery denervation as compared with a sham control.
- 14. Ramipril and Telmisartan in combination associated with increased risk of AKI
- 15. Tight blood pressure control in patients with hypertension & type 2 diabetes achieves a clinically important reduction in the risk of deaths related to diabetes, complications related to diabetes, progression of diabetic retinopathy & deterioration in visual acuity.
- 16. Reduction in all-cause and cardiovascular mortality with more intensive BP target (SBP less than 120mmHg)
Down
- 1. Compared with doxazosin, chlorthalidone yields essentially equal risk of CHD death/nonfatal MI but significantly reduces the risk of combined CVD events, particularly CHF, in high-risk hypertensive patients.
- 3. AOBP is more accurate than office BP
- 5. Perindopril and indapamide reduce BP 12/5 & significantly reduce rate of stroke in normal and hypertensive patients with previous stroke/TIA.
- 7. No additional benefit of slowing progression of hypertensive nephrosclerosis was observed in African-Americans with the lower BP goal, but still some additional reduction in proteinuria.
- 8. Candesartan 16 mg once daily is as effective as lisinopril 20 mg once daily in reducing blood pressure and microalbuminuria in hypertensive pts with type 2 diabetes.
- 9. No benefit in diabetic kidney disease for combined ACE inhibitor and ARB
- 11. Among elderly patients with isolated systolic hypertension, antihypertensive drug treatment starting with nitrendipine reduces the rate of cardiovascular complications.
- 13. Treatment of the patients older than 80 years remains beneficial with diuretic with or without ACE inhibitor.