Across
- 3. Emerging multidrug-resistant yeast causing healthcare-associated outbreaks
- 6. Initial test guiding early empiric antimicrobial therapy
- 7. Preventive antimicrobial strategy in high-risk patients
- 8. Diagnostic gold standard for confirming osteomyelitis before prolonged therapy
- 10. Adjustment of antibiotics based on culture results rather than clinical improvement alone
- 11. Disposition strategy for a stable patient requiring prolonged intravenous therapy after hospital discharge
- 12. Most important intervention in a patient with abscess who is not improving on appropriate antibiotics
- 13. Organism associated with hypermucoviscous liver abscess in certain populations
- 15. Encapsulated yeast causing meningitis in immunocompromised hosts
- 20. Positive culture without clinical signs of infection that should not prompt treatment
- 21. Laboratory data used to determine the most appropriate targeted antibiotic
- 22. Alternative to vancomycin for MRSA bacteremia that cannot be used in pneumonia
- 24. Rapid diagnostic modality used when cultures are negative but suspicion remains high
- 26. Escalation agent for severe infections caused by ESBL-producing organisms
- 29. Broad empiric therapy often de-escalated once culture data are available
- 30. Organism frequently resistant to vancomycin in hospitalized patients
- 32. Resistance mechanism suspected when ceftriaxone fails in a gram-negative bacteremia
- 33. Biomarker sometimes used to support early discontinuation of antibiotics
Down
- 1. Oral option for MRSA with excellent bioavailability but risk of thrombocytopenia
- 2. New infection that develops during treatment of an existing one
- 4. Patient with bacteremia and persistent fevers despite antibiotics requires evaluation for this organism’s metastatic complications
- 5. Pathogen to consider in hospital-acquired infections with intrinsic resistance patterns
- 9. First-line therapy for MRSA bacteremia requiring drug level monitoring to avoid nephrotoxicity
- 14. Marker used to assess severity and prognosis in sepsis
- 15. Preferred therapy for MSSA bacteremia despite availability of broader-spectrum agents
- 16. Preferred imaging when transthoracic study is negative but suspicion for valvular infection remains high
- 17. Blood culture result often due to skin flora in a single bottle without clinical correlation
- 18. Hospital-specific data used to guide empiric antibiotic selection
- 19. Diagnosis that must be excluded in all patients with Staphylococcus aureus bacteremia using repeat cultures and imaging
- 23. Mold causing angioinvasive disease in neutropenic patients
- 25. Test that must be repeated to document clearance in bacteremia
- 27. Mechanism explaining persistent infection on prosthetic material despite appropriate antibiotics
- 28. Enzyme that renders carbapenems ineffective in multidrug-resistant organisms
- 31. Syndrome defined by infection plus organ dysfunction